Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620985 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL5186832 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL620986 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL16139792 | 0.89 | TSHR (0.33) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL2404099 | 0.89 | TSHR (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL108106 | 0.89 | TSHR (0.33) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL16139789 | 0.89 | TSHR (0.33) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL14770948 | 0.87 | TRPV1 (0.32) | TRPV1TRPA1TSHRTDP1 | |
| SCHEMBL14771122 | 0.87 | TRPV1 (0.32) | TRPV1TRPA1TSHRTDP1 | |
| SCHEMBL14770951 | 0.87 | TRPV1 (0.32) | TRPV1TRPA1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403953-B1 | METHOD FOR STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | CAMBREX IEP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9045780-B2 | Process for the stereoselective enzymatic reduction of keto compounds | IEP GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20120040425-A1 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| EP-2226386-A1 | Method for stereoselective enzymatic reduction of keto compounds | IEP GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |