Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186832 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL620984 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL620986 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL16139792 | 0.89 | TSHR (0.33) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL2404099 | 0.89 | TSHR (0.39) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL108106 | 0.89 | TSHR (0.33) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL16139789 | 0.89 | TSHR (0.33) | ALDH1A1LMNATRPV1TRPA1TSHR | |
| SCHEMBL14770948 | 0.87 | TRPV1 (0.32) | TRPV1TRPA1TSHRTDP1 | |
| SCHEMBL14771122 | 0.87 | TRPV1 (0.32) | TRPV1TRPA1TSHRTDP1 | |
| SCHEMBL14770951 | 0.87 | TRPV1 (0.32) | TRPV1TRPA1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085334-A1 | ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2026-03-26 | — | — | US | disclosed |
| EP-4551693-A1 | ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF | Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) | 2025-05-14 | — | — | EP | disclosed |
| CN-117384868-A | Engineered ketoreductase and method for preparing chiral alcohol compounds | 宁波酶赛生物工程有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2024001593-A1 | ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2024-01-04 | — | — | WO | disclosed |
| EP-2403953-B1 | METHOD FOR STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | CAMBREX IEP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9045780-B2 | Process for the stereoselective enzymatic reduction of keto compounds | IEP GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20120040425-A1 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| EP-2403953-A1 | METHOD FOR STEREOSELECTIVELY AND ENZYMATICALLY REDUCING KETO COMPOUNDS | IEP GmbH (DE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100195-A1 | METHOD FOR STEREOSELECTIVELY AND ENZYMATICALLY REDUCING KETO COMPOUNDS | IEP GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |
| EP-2226386-A1 | Method for stereoselective enzymatic reduction of keto compounds | IEP GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |
| US-5565593-A | FERROCENYL-1,1'-BIS(DIETHYPHOSPHONITE); CHEMICAL INTERMEDIATES FOR PREPERATION OF PHOSPHOLANE LIGANDS AND CHIRAL COMPLEXES, USEFUL AS CATALYSTS FOR CARRYING OUT ENANTIOSELECTIVE REACTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| US-5559267-A | ENANTIOMORPHS, STEREOCHEMICAL CONTROL AND ASSYMETRIC INDUCTION, HYDROGENATION OF UNSATURATED ESTERS, COORDINATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| US-5543571-A | Preparation of optically active hydrazines and amines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-06 | — | — | US | disclosed |
| US-5532395-A | HYDROGENATION CATALYSTS ) | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-07-02 | — | — | US | disclosed |
| US-5426223-A | Hydrogenation of n-acyl hydrazones in presence of catalyst comprising complex pf transition metal bonded to phosphine ligands | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| US-5386061-A | Reacting a bis(primary phosphine in the presence of a strong base with a cyclic sulfate; cyclization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| US-5329015-A | Catalysts for stereospecific reactions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5250731-A | Asymmetric hydrogenation of N-acylhydrazones to N-acylhydrazines in presence of chiral phospholane complex | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| WO-1993001199-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5171892-A | Chiral phospholanes via chiral 1,4-diol cyclic sulfates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085334-A1 | ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF | ADH1A, CYP4F11, ADH1C | ALDH1A1 147/4885LMNA 4016/4885TRPV1 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.