Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210619 | 0.93 | KMT2A (0.45) | CTSKLMNAKMT2AMEN1EPHX2 | |
| SCHEMBL6210442 | 0.92 | CTSK (0.52) | CTSKLMNAKMT2AMEN1CTSL | |
| SCHEMBL6210543 | 0.91 | CTSK (0.44) | CTSKKMT2AMEN1CCR5NAMPT | |
| SCHEMBL6212228 | 0.90 | CTSK (0.42) | CTSKKMT2AMEN1CTSLCTSS | |
| SCHEMBL6210377 | 0.90 | CTSK (0.40) | CTSKKMT2AMEN1EPHX2CTSL | |
| SCHEMBL6211096 | 0.90 | CTSK (0.44) | CTSKKMT2AMEN1CTSLCTSS | |
| SCHEMBL6211885 | 0.89 | RAB9A (0.44) | CTSKKMT2AMEN1CTSLCTSS | |
| SCHEMBL6210632 | 0.89 | CTSK (0.40) | CTSKKMT2AMEN1CTSLCTSS | |
| SCHEMBL6211900 | 0.88 | TLR7 (0.42) | CTSKKMT2ACCR5 | |
| SCHEMBL6211690 | 0.88 | CTSK (0.39) | CTSKKMT2AMEN1KDM5ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |