Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.50 |
| ▸ | CTSL | P07711 | 10/20 | 0.42 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235462 | 0.92 | CCR1 (0.46) | CTSKCTSLCTSSCTSBDRD4 | |
| SCHEMBL4042607 | 0.91 | CTSK (0.53) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4051552 | 0.91 | CTSK (0.58) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4046358 | 0.90 | CTSK (0.54) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4043681 | 0.90 | CTSK (0.52) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4038859 | 0.89 | CTSK (0.53) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4039586 | 0.89 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4051956 | 0.89 | CTSK (0.41) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4043273 | 0.88 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4041699 | 0.88 | CTSK (0.56) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |