Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 8/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212034 | 0.85 | CYP1A2 (0.41) | WNT3AALDH1A1MAPT | |
| SCHEMBL6215690 | 0.81 | WNT3A (0.47) | WNT3AALDH1A1 | |
| SCHEMBL6210153 | 0.81 | WNT3A (0.43) | WNT3AMAPTHTR6DRD4HTR2A | |
| SCHEMBL7248437 | 0.80 | MAPK1 (0.47) | ALDH1A1MAPTLMNA | |
| SCHEMBL6212859 | 0.80 | DRD2 (0.45) | WNT3AALDH1A1DRD4 | |
| SCHEMBL6214370 | 0.79 | DRD4 (0.45) | WNT3ACDK9CCNT1LMNADRD4 | |
| SCHEMBL6212381 | 0.78 | MEN1 (0.46) | WNT3AALDH1A1MAPTLMNA | |
| SCHEMBL6214919 | 0.77 | KMT2A (0.43) | ALDH1A1LMNA | |
| SCHEMBL6211122 | 0.77 | MEN1 (0.43) | WNT3ALMNADRD4 | |
| SCHEMBL6216012 | 0.77 | DRD4 (0.41) | WNT3AALDH1A1MAPTHTR6DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |