Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6336428 | 0.94 | HPGD (0.47) | HPGDMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6211134 | 0.79 | HPGD (0.39) | HPGDMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL669860 | 0.77 | KCNH2 (0.30) | KCNH2OPRM1OPRD1MRGPRX2CHRM3 | |
| SCHEMBL15370923 | 0.77 | KCNH2 (0.30) | KCNH2OPRM1OPRD1MRGPRX2CHRM3 | |
| SCHEMBL668761 | 0.77 | KCNH2 (0.30) | KCNH2OPRM1OPRD1MRGPRX2CHRM3 | |
| SCHEMBL11240083 | 0.75 | HPGD (0.47) | HPGDKCNH2HTR2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6906945 | 0.75 | HTT (0.32) | OPRM1OPRD1TSHRNPC1RAB9A | |
| SCHEMBL15688853 | 0.74 | HPGD (0.46) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10140576 | 0.73 | KMT2A (0.57) | HPGDKCNH2HTR2AADRA1AOPRK1 | |
| SCHEMBL19047046 | 0.73 | ALDH1A1 (0.50) | HPGDMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507521-A1 | METABOLITE OF 1-DIMETHYLAMINO-3-(3-METHOXY-PHENYL)-2-METHYL-PENTANE-3-OL AND THE USE THEREOF IN THE TREATMENT OF URINARY INCONTINENCE | Grünenthal GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003101440-A1 | METABOLITE OF 1-DIMETHYLAMINO-3-(3-METHOXY-PHENYL)-2-METHYL-PENTANE-3-OL AND THE USE THEREOF IN THE TREATMENT OF URINARY INCONTINENCE | Grünenthal GmbH (DE) | 2003-12-11 | — | — | WO | disclosed |