Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13562587 | 0.81 | ACKR3 (0.46) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6336428 | 0.80 | HPGD (0.47) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9683311 | 0.79 | NPC1 (0.64) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL6726553 | 0.79 | NPC1 (0.64) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL15688853 | 0.79 | HPGD (0.46) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL19047046 | 0.78 | ALDH1A1 (0.50) | HPGDKMT2AMEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL9324495 | 0.77 | MAPT (0.67) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL8728688 | 0.77 | MDM2 (0.66) | HPGDPGRADRA2AADRA2BHTR2A | |
| SCHEMBL8728691 | 0.77 | MDM2 (0.66) | HPGDPGRADRA2AADRA2BHTR2A | |
| SCHEMBL8284080 | 0.76 | POLB (0.51) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313896-A | ANTIDEPRESSANTS, PSYCHOTROPIC AGENTS | ELI LILLY AND COMPANY (US) | 1982-02-02 | — | — | US | disclosed |