Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112305 | 0.92 | TGFBR1 (0.36) | TGFBR1KDM4EMAPK1HIF1ATDP1 | |
| Hydrochloric Acid SCHEMBL22341966 | 0.90 | TGFBR1 (0.35) | TGFBR1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL17308698 | 0.86 | TGFBR1 (0.33) | TGFBR1KDM4E | |
| SCHEMBL109677 | 0.83 | KDM4E (0.44) | TGFBR1KDM4EMAPK1HIF1A | |
| SCHEMBL316224 | 0.82 | TGFBR1 (0.41) | TGFBR1KDM4EMAPK1HIF1ATDP1 | |
| SCHEMBL4330261 | 0.82 | KDM4E (0.48) | KDM4EMAPK1HIF1A | |
| SCHEMBL4324661 | 0.82 | KDM4E (0.48) | KDM4EMAPK1HIF1A | |
| Sulfuric Acid SCHEMBL11210945 | 0.82 | EPHX1 (0.41) | TGFBR1KDM4EMAPK1HIF1ALMNA | |
| SCHEMBL11866190 | 0.81 | TGFBR1 (0.38) | TGFBR1KDM4EMAPK1HIF1ATDP1 | |
| Iodide SCHEMBL30637250 | 0.80 | KDM4E (0.46) | KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507564-A1 | WATER-ABSORBING POLYMER PARTICLES INHIBITING THE BREAKDOWN OF BODY FLUIDS, COMPOSITES COMPRISING THE SAME AND USE THEREOF | Stockhausen GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003090799-A1 | WATER-ABSORBING POLYMER PARTICLES INHIBITING THE BREAKDOWN OF BODY FLUIDS, COMPOSITES COMPRISING THE SAME AND USE THEREOF | STOCKHAUSEN GMBH (DE) | 2003-11-06 | — | — | WO | disclosed |