SCHEMBL6212017

SCHEMBL6212017

CC(C)(C)OC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCCC3=O)C(=O)O1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F10 P00742 9/20 0.48
MAOA P21397 4/20 0.44
MAOB P27338 3/20 0.44
LMNA P02545 1/20 0.44
PTGS1 P23219 1/20 0.44
CALML3 P27482 1/20 0.44
SDHA P31040 1/20 0.44
GPR119 Q8TDV5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6212022 1.00 F10 (0.48) F10MAOAMAOBLMNAPTGS1
SCHEMBL6481289 0.87 F10 (0.45) F10MAOAMAOBLMNAPTGS1
SCHEMBL6481292 0.87 F10 (0.45) F10MAOAMAOBLMNAPTGS1
SCHEMBL6194275 0.86 MAOA (0.57) F10MAOAMAOBLMNAPTGS1
SCHEMBL6191933 0.86 MAOA (0.57) F10MAOAMAOBLMNAPTGS1
SCHEMBL6213354 0.85 F10 (0.44) F10MAOAMAOBLMNAPTGS1
SCHEMBL6242604 0.85 F10 (0.44) F10MAOAMAOBLMNAPTGS1
SCHEMBL6242612 0.85 F10 (0.44) F10MAOAMAOBLMNAPTGS1
SCHEMBL9447588 0.84 MAOA (0.57) F10MAOAMAOBLMNAPTGS1
SCHEMBL9447577 0.84 MAOA (0.57) F10MAOAMAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288273-A1 Antibacterial agents BOYER FREDERICK E JR 2005-12-29 US disclosed
EP-1594865-A2 ANTIBACTERIAL AGENTS Warner-Lambert Company LLC (US) 2005-11-16 EP disclosed
WO-2004069832-A2 ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY LLC (US) 2004-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288273-A1 Antibacterial agents MRPL21, RPN2, FBL F10 2894/4885MAOA 236/4885MAOB 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.