Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964327 | 0.90 | CNR2 (0.57) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL6212084 | 0.89 | MEN1 (0.59) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL6212990 | 0.86 | MEN1 (0.56) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL5963956 | 0.83 | CNR2 (0.53) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL5964260 | 0.79 | CNR2 (0.60) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL5964288 | 0.78 | CNR2 (0.67) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL5964761 | 0.78 | MEN1 (0.52) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL5964591 | 0.78 | MEN1 (0.48) | MEN1KMT2ACNR2GAAMAPK1 | |
| SCHEMBL6275388 | 0.76 | KMT2A (0.52) | MEN1KMT2APRMT5WDR77CYP2D6 | |
| SCHEMBL6194878 | 0.76 | CNR2 (0.77) | MEN1KMT2ACNR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | disclosed |