Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212510 | 0.79 | KMT2A (0.58) | KMT2AMEN1RAB9ACYP2D6ADRB2 | |
| SCHEMBL6212413 | 0.76 | MEN1 (0.52) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11592418 | 0.73 | KMT2A (0.53) | KMT2AMEN1RAB9ACYP2D6ADRB2 | |
| Hydrochloric Acid SCHEMBL11593188 | 0.72 | KMT2A (0.55) | KMT2AMEN1RAB9ACYP2D6ADRB2 | |
| SCHEMBL4196759 | 0.69 | KMT2A (0.53) | KMT2AMEN1RAB9ACYP2D6CYP2C9 | |
| SCHEMBL5964327 | 0.69 | CNR2 (0.57) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5022877 | 0.69 | KCNH2 (0.52) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6210889 | 0.69 | PPARG (0.51) | KMT2AMEN1NPSR1 | |
| SCHEMBL28752321 | 0.68 | AKR1C3 (0.56) | KMT2AMEN1AKR1C3AKR1C2CYP2C9 | |
| Hydrochloric Acid SCHEMBL4358412 | 0.68 | KCNH2 (0.63) | KMT2AMEN1CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | disclosed |