Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.66 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 2/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | DRD3 | P35462 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28690097 | 0.98 | L3MBTL3 (0.64) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| SCHEMBL13990656 | 0.98 | L3MBTL3 (0.68) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| SCHEMBL3285312 | 0.95 | DRD2 (0.65) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| Hydrochloric Acid SCHEMBL4324912 | 0.93 | DRD2 (0.63) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| SCHEMBL24163317 | 0.92 | RECQL (0.69) | L3MBTL3MBTD1TSHRRECQLALDH1A1 | |
| SCHEMBL6584141 | 0.90 | DRD2 (0.55) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| SCHEMBL2322360 | 0.90 | DRD2 (0.55) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| SCHEMBL5052507 | 0.90 | L3MBTL3 (0.59) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| SCHEMBL4278988 | 0.90 | DRD2 (0.55) | L3MBTL3MBTD1L3MBTL1TSHRRECQL | |
| SCHEMBL5050001 | 0.90 | L3MBTL3 (0.59) | L3MBTL3MBTD1L3MBTL1TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1583742-A | Method for preparing 4-piperidyl piperidine | UNIV TONGJI (CN) | 2005-02-23 | — | — | CN | claimed |
| JP-63141964-A | — | — | None | — | — | JP | disclosed |
| US-6900244-B2 | Anilino liver X-receptor modulators | PHARMACIA CORPORATION (US) | 2005-05-31 | — | — | US | disclosed |
| CN-1611499-A | Heterocyclic compounds as inhibitors of rotamase enzymes | PFIZER (US) | 2005-05-04 | — | — | CN | disclosed |
| EP-1509495-A1 | ANILINO LIVER X-RECEPTOR MODULATORS | Pharmacia Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| CN-1583742-A | Method for preparing 4-piperidyl piperidine | UNIV TONGJI (CN) | 2005-02-23 | — | — | CN | disclosed |
| CN-1174978-C | Heterocyclic compounds useful as rotamase inhibitors | — | 2004-11-10 | — | — | CN | disclosed |
| CN-1511837-A | Intermediate for heterocyclic compound in preparing rotamase inhibitor | — | 2004-07-14 | — | — | CN | disclosed |
| US-20040087632-A1 | Controlling metabolism of lipids, cholesterol | PHARMACIA CORPORATION | 2004-05-06 | — | — | US | disclosed |
| WO-2003099769-A1 | ANILINO LIVER X-RECEPTOR MODULATORS | PHARMACIA CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |
| JP-S63141964-A | PRODUCTION OF 4-PIPERIDINOPIPERIDINES | KOEI CHEM CO LTD | 1988-06-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087632-A1 | Controlling metabolism of lipids, cholesterol | NR1H2, NR1H3, SREBF1 | L3MBTL3 3117/4885MBTD1 2377/4885L3MBTL1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.