Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214058 | 0.88 | MMP13 (0.54) | MMP13PPARGLMNAPOLBRXFP1 | |
| SCHEMBL6724632 | 0.83 | MMP13 (0.53) | MMP13PPARGLMNAPOLBRXFP1 | |
| SCHEMBL6213632 | 0.82 | ALDH1A1 (0.53) | MMP13RXFP1MAPTROCK2 | |
| SCHEMBL6212989 | 0.82 | MMP13 (0.54) | MMP13PPARGLMNAPOLBRXFP1 | |
| SCHEMBL6212954 | 0.82 | MMP13 (0.60) | MMP13PPARGLMNAPOLBRXFP1 | |
| SCHEMBL6213923 | 0.80 | MMP13 (0.54) | MMP13PPARGLMNAPOLBRXFP1 | |
| SCHEMBL6213708 | 0.78 | MMP13 (0.52) | MMP13PPARGLMNAPOLBRXFP1 | |
| SCHEMBL6212605 | 0.78 | PIK3CA (0.46) | MMP13RXFP1MAPTROCK2 | |
| SCHEMBL6234634 | 0.77 | MMP13 (0.58) | MMP13PPARGLMNAPOLBRXFP1 | |
| SCHEMBL6213391 | 0.76 | PPARG (0.54) | MMP13PPARGLMNAPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362048-B1 | TRIAZOLO COMPOUNDS AS MMP INHIBITORS | WARNER LAMBERT CO (US) | 2005-05-04 | — | — | EP | claimed |