Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217049 | 0.83 | ADORA2B (0.52) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL6218229 | 0.82 | ADORA2B (0.53) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL6217412 | 0.76 | ADORA2B (0.46) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL4052034 | 0.75 | ADORA2B (0.66) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4054170 | 0.74 | ADORA2B (0.74) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL6268781 | 0.73 | ADORA2B (0.59) | ADORA2BADORA2AKMT2AMEN1ADORA1 | |
| SCHEMBL7030304 | 0.72 | KMT2A (0.74) | ADORA2BADORA2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL6215448 | 0.72 | ADORA2B (0.51) | ADORA2BADORA2AADORA1ADORA3ALDH1A1 | |
| SCHEMBL7023315 | 0.72 | KMT2A (0.78) | ADORA2BADORA2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4058134 | 0.72 | ADORA2B (0.72) | ADORA2BADORA2AKMT2AMEN1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492793-A1 | NEW-4-(PYRROLOPYRIMIDIN-6-YL)BENZENESULPHONAMIDE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082873-A1 | NEW-4-(PYRROLOPYRIMIDIN-6-YL)BENZENESULPHONAMIDE DERIVATIVES | ALMIRALL PRODESFARMA, S.A. (ES) | 2003-10-09 | — | — | WO | disclosed |