Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 12/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218229 | 0.88 | ADORA2B (0.53) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL6213809 | 0.83 | ADORA2B (0.51) | ADORA2BADORA2AALDH1A1ADORA1TSHR | |
| SCHEMBL6268781 | 0.79 | ADORA2B (0.59) | ADORA2BADORA2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6215790 | 0.77 | ADORA2B (0.57) | ADORA2BADORA2ALMNAADORA1TSHR | |
| SCHEMBL6217649 | 0.76 | ADORA2B (0.57) | ADORA2BADORA2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4060729 | 0.76 | ADORA2B (0.70) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL6214870 | 0.76 | ADORA2B (0.57) | ADORA2BADORA2AALDH1A1SMN1; SMN2ADORA1 | |
| SCHEMBL4059961 | 0.75 | ADORA2B (0.79) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4049547 | 0.75 | ADORA2B (0.74) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL6217412 | 0.74 | ADORA2B (0.46) | ADORA2BADORA2ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492793-A1 | NEW-4-(PYRROLOPYRIMIDIN-6-YL)BENZENESULPHONAMIDE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082873-A1 | NEW-4-(PYRROLOPYRIMIDIN-6-YL)BENZENESULPHONAMIDE DERIVATIVES | ALMIRALL PRODESFARMA, S.A. (ES) | 2003-10-09 | — | — | WO | disclosed |