Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210782 | 0.89 | CTSK (0.42) | CTSKCTSLCTSSCTSV | |
| SCHEMBL6212810 | 0.87 | CTSK (0.40) | CTSKCTSLCTSSCTSV | |
| SCHEMBL6213828 | 0.85 | CTSK (0.57) | CTSKCTSLCTSS | |
| SCHEMBL4041432 | 0.83 | CTSK (0.44) | CTSKCTSLCTSSCTSV | |
| SCHEMBL4044478 | 0.82 | CTSK (0.42) | CTSKCTSLCTSS | |
| SCHEMBL6212234 | 0.82 | CTSK (0.51) | CTSKCTSLCTSSCTSV | |
| SCHEMBL4042168 | 0.82 | CTSK (0.42) | CTSKCTSLCTSSCTSV | |
| SCHEMBL4046473 | 0.81 | CTSK (0.43) | CTSKCTSLCTSSCTSV | |
| SCHEMBL6210372 | 0.80 | CTSK (0.52) | CTSKCTSLCTSS | |
| SCHEMBL6210043 | 0.80 | CTSK (0.51) | CTSKCTSLCTSSCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |