SCHEMBL621440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL620821	0.82	IDO1 (0.46)	TBXAS1MAPTLMNATSHRHTT
	SCHEMBL618316	0.78	CYP1A2 (0.50)	MAPTHTTALDH1A1MAPK1HSD17B10
	SCHEMBL3807595	0.77	NPC1 (0.44)	MAPTLMNATSHRHTTALDH1A1
	SCHEMBL2414599	0.77	CYP1A2 (0.62)	MAPTLMNAALDH1A1HSD17B10NPC1
	SCHEMBL4976461	0.77	HTR1B (0.42)	MAPTLMNATSHRHTTALDH1A1
	SCHEMBL2416844	0.77	CYP1A2 (0.41)	MAPTLMNATSHRHTTALDH1A1
	SCHEMBL620780	0.77	NPC1 (0.47)	MAPTLMNAHTTALDH1A1MAPK1
	SCHEMBL3378946	0.77	DRD1 (0.50)	MAPTTSHRHTTALDH1A1ALOX15
	SCHEMBL2415489	0.76	CYP1A2 (0.56)	MAPTLMNATSHRALDH1A1HSD17B10
	SCHEMBL2418152	0.76	CYP1A2 (0.44)	MAPTLMNATSHRHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.