Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CALML3 | P27482 | 1/20 | 0.38 |
| ▸ | SDHA | P31040 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208617 | 0.88 | NPC1 (0.42) | F10GRM2 | |
| SCHEMBL6192456 | 0.82 | GRM2 (0.39) | MAOBMAOACALML3GRM2 | |
| SCHEMBL6209091 | 0.82 | GRM2 (0.39) | MAOBMAOACALML3GRM2 | |
| SCHEMBL6192191 | 0.80 | GRM2 (0.39) | MAOBMAOACALML3GRM2 | |
| SCHEMBL6212026 | 0.80 | GRM2 (0.39) | MAOBMAOACALML3GRM2 | |
| SCHEMBL6961081 | 0.80 | MAOB (0.41) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8118120 | 0.79 | MAOB (0.41) | MAOBF10MAOAGRM2 | |
| SCHEMBL14334837 | 0.78 | TMEM97 (0.39) | MAOBF10MAOAGRM2 | |
| SCHEMBL8144891 | 0.77 | ATAD2 (0.46) | MAOBMAOAGRM2 | |
| SCHEMBL7485004 | 0.77 | MAOB (0.57) | MAOBF10MAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594494-A1 | OXAZOLIDINONE DERIVATIVES N-SUBSTITUTED BY A BICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069244-A1 | OXAZOLIDINONE DERIVATIVES N-SUBSTITUTED BY A BICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-19 | — | — | WO | disclosed |