Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217886 | 0.90 | ACHE (0.39) | KMT2AALDH1A1ACHEHSD17B10GAA | |
| SCHEMBL6246108 | 0.90 | SMN1; SMN2 (0.51) | KMT2AALDH1A1ACHEHSD17B10GAA | |
| SCHEMBL6219804 | 0.88 | HSD17B10 (0.45) | KMT2AALDH1A1ACHEHSD17B10GAA | |
| SCHEMBL6217771 | 0.87 | ACHE (0.53) | ALDH1A1ACHEKDM4ERPS6KA2 | |
| SCHEMBL6697366 | 0.87 | SMN1; SMN2 (0.47) | KMT2AALDH1A1ACHEHSD17B10GAA | |
| SCHEMBL6667667 | 0.80 | ACHE (0.46) | ACHE | |
| SCHEMBL5781219 | 0.80 | ACHE (0.39) | KMT2AALDH1A1ACHEGAAHPGD | |
| SCHEMBL6217619 | 0.80 | ACHE (0.42) | KMT2AALDH1A1ACHEHSD17B10GAA | |
| SCHEMBL6667214 | 0.79 | KMT2A (0.43) | KMT2AALDH1A1ACHEHSD17B10GAA | |
| SCHEMBL6217132 | 0.79 | ACHE (0.57) | ACHERPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414817-B1 | substituted isoindoles and the use thereof | BAYER HEALTHCARE AG (DE) | 2005-04-06 | — | — | EP | disclosed |