Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LHCGR | P22888 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216455 | 0.89 | LHCGR (0.59) | MAPTMEN1KMT2ATDP1LHCGR | |
| SCHEMBL4899220 | 0.88 | BRAF (0.61) | MAPTMEN1KMT2ATDP1LHCGR | |
| SCHEMBL6214606 | 0.88 | LHCGR (0.57) | MAPTTDP1LHCGRTSHRIKBKB | |
| SCHEMBL6217388 | 0.87 | LHCGR (0.59) | MAPTMEN1KMT2ALHCGRTSHR | |
| SCHEMBL2133864 | 0.87 | LHCGR (0.60) | MAPTMEN1KMT2ATDP1LHCGR | |
| SCHEMBL6216798 | 0.85 | LHCGR (0.52) | MAPTKMT2ALHCGRTSHRIKBKB | |
| SCHEMBL4908873 | 0.84 | LHCGR (0.55) | MAPTMEN1KMT2ATDP1LHCGR | |
| SCHEMBL5025967 | 0.82 | LHCGR (0.62) | MAPTMEN1KMT2ATDP1LHCGR | |
| SCHEMBL6217652 | 0.81 | LIMK1 (0.58) | MAPTMEN1KMT2ALHCGRTSHR | |
| SCHEMBL27490182 | 0.80 | MAPT (0.65) | MAPTMEN1KMT2ATDP1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171443-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS USEFUL AS LH AGONISTS | AKZO NOBEL NV (NL) | 2005-07-13 | — | — | EP | claimed |