Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 11/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.33 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309511 | 0.89 | ACHE (0.39) | ACHEALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL6216886 | 0.89 | ACHE (0.35) | ACHEALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL4314756 | 0.84 | KDM4E (0.40) | ALDH1A1ACKR3KDM4E | |
| SCHEMBL6216144 | 0.78 | ACHE (0.39) | ACHEALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL6216650 | 0.76 | ALDH1A1 (0.38) | ACHEALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL4304883 | 0.71 | CHRM3 (0.42) | ALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL4309831 | 0.68 | ACHE (0.61) | ACHEALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL4302308 | 0.68 | ACHE (0.56) | ACHEALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL4303895 | 0.68 | F10 (0.56) | ACHEALDH1A1HPGDSMN1; SMN2F10 | |
| SCHEMBL13950124 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2F10ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414817-B1 | substituted isoindoles and the use thereof | BAYER HEALTHCARE AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| EP-1414817-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | Bayer HealthCare AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011858-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-02-13 | — | — | WO | disclosed |