Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SDCBP | O00560 | 2/20 | 0.43 |
| ▸ | SDC2 | P34741 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445088 | 1.00 | EPHX2 (0.50) | EPHX2PLA2G2APLA2G5TSHRFAAH | |
| SCHEMBL6445084 | 1.00 | EPHX2 (0.50) | EPHX2PLA2G2APLA2G5TSHRFAAH | |
| SCHEMBL621625 | 1.00 | EPHX2 (0.50) | EPHX2PLA2G2APLA2G5TSHRFAAH | |
| SCHEMBL6446232 | 0.98 | EPHX2 (0.48) | EPHX2PLA2G2APLA2G5TSHRFAAH | |
| SCHEMBL622468 | 0.98 | EPHX2 (0.48) | EPHX2PLA2G2APLA2G5TSHRFAAH | |
| SCHEMBL6444837 | 0.92 | EPHX2 (0.44) | EPHX2PLA2G2APLA2G5TSHRSDCBP | |
| SCHEMBL28345864 | 0.89 | TSHR (0.44) | EPHX2PLA2G2APLA2G5TSHRFAAH | |
| SCHEMBL28345863 | 0.89 | TSHR (0.44) | EPHX2PLA2G2APLA2G5TSHRFAAH | |
| SCHEMBL15623788 | 0.88 | PLA2G2A (0.56) | EPHX2PLA2G2APLA2G5FAAHMEN1 | |
| SCHEMBL28806410 | 0.85 | TSHR (0.47) | TSHRFAAHMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |