Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SDCBP | O00560 | 2/20 | 0.40 |
| ▸ | SDC2 | P34741 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446232 | 0.94 | EPHX2 (0.48) | EPHX2PLA2G2APLA2G5TSHRSDCBP | |
| SCHEMBL622468 | 0.94 | EPHX2 (0.48) | EPHX2PLA2G2APLA2G5TSHRSDCBP | |
| SCHEMBL621624 | 0.92 | EPHX2 (0.50) | EPHX2PLA2G2APLA2G5TSHRSDCBP | |
| SCHEMBL621625 | 0.92 | EPHX2 (0.50) | EPHX2PLA2G2APLA2G5TSHRSDCBP | |
| SCHEMBL6445084 | 0.92 | EPHX2 (0.50) | EPHX2PLA2G2APLA2G5TSHRSDCBP | |
| SCHEMBL6445088 | 0.92 | EPHX2 (0.50) | EPHX2PLA2G2APLA2G5TSHRSDCBP | |
| SCHEMBL18924154 | 0.90 | FAAH (0.43) | EPHX2TSHRALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL17570945 | 0.90 | FAAH (0.43) | EPHX2TSHRALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL464264 | 0.86 | CTSS (0.43) | EPHX2PLA2G2APLA2G5SDCBPSDC2 | |
| SCHEMBL12012827 | 0.85 | EPHX2 (0.40) | EPHX2PLA2G2APLA2G5SDCBPSDC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839798-B1 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LAB (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-0402646-B1 | Retroviral protease inhibiting compounds | ABBOTT LAB (US) | 1998-07-22 | — | — | EP | disclosed |
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |