⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388497 | 0.72 | — | — | |
| SCHEMBL13862155 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL992411 | 0.69 | — | — | |
| SCHEMBL172783 | 0.69 | — | — | |
| SCHEMBL856276 | 0.69 | — | — | |
| SCHEMBL28270615 | 0.69 | ALDH1A1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL28031350 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL1454569 | 0.69 | — | — | |
| SCHEMBL15751044 | 0.67 | — | — | |
| SCHEMBL13820416 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189951-B1 | NEW PROCESS FOR THE PREPARATION OF CERTAIN STEROIDS, ESPECIALLY INTERMEDIATES FOR THE PREPARATION OF PROLIGESTONE AND RELATED COMPOUNDS, AND NEW INTERMEDIATES FORMED IN THIS PROCESS | AKZO N.V. (NL) | 1989-09-20 | — | — | EP | claimed |
| EP-0189951-A1 | New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process | AKZO N.V. (NL) | 1986-08-06 | — | — | EP | claimed |
| EP-0188010-A1 | New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process | GIST-BROCADES N.V. (NL) | 1986-07-23 | — | — | EP | claimed |
| EP-2445874-B1 | PROCESS OF PREPARATION OF 2-ACETYL-1-PYRROLINE AND A STABLE PRECURSOR THEREOF, ISOTOPICALLY LABELLED OR NOT | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-11-29 | — | — | EP | disclosed |
| WO-2017175064-A1 | BIOENZYMATIC SYNTHESIS OF TETRAHYDROCANNABIVARIN (THC-V), CANNABINOL (CBN), AND CANNABIVARIN (CBV) AND THEIR USE AS THERAPEUTIC AGENTS | FULL SPECTRUM LABORATORIES LTD (IE) | 2017-10-12 | — | — | WO | disclosed |
| US-20170283837-A1 | BIOENZYMATIC SYNTHESIS OF THC-v, CBV AND CBN AND THEIR USE AS THERAPEUTIC AGENTS | TUATARA CAPITAL FUND I, L.P. | 2017-10-05 | — | — | US | disclosed |
| US-20150322012-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | AVENUE CAPITAL MANAGEMENT II, L.P. | 2015-11-12 | — | — | US | disclosed |
| EP-2421873-B1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2014-07-02 | — | — | EP | disclosed |
| US-8597706-B2 | Method for synthesizing 2-acetyl-1-pyrroline, stable ketal precursors thereof, and isotopically marked analogs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-12-03 | — | — | US | disclosed |
| US-8182781-B2 | Alpha-silyl alcohols possessing olfactory properties reminiscent of patchouli oil | GIVAUDAN S.A. (CH) | 2012-05-22 | — | — | US | disclosed |
| EP-2445874-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | Centre National De La Recherche Scientifique CNRS (FR) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010121979-A1 | ALPHA-SILYL ALCOHOLS POSSESSING OLFACTORY PROPERTIES REMINISCENT OF PATCHOULI OIL | GIVAUDAN SA (CH) | 2010-10-28 | — | — | WO | disclosed |
| US-7629494-B2 | Process for producing cyclopropylphenol derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20090054681-A1 | Production Process of cyclopropylphenol derivatives | SANKYO AGRO COMPANY, LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1880987-A1 | PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE | Sankyo Agro Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
| WO-2002012187-A1 | NOVEL PHENYLHETEROAZETIDINES, USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | WO | disclosed |
| CN-1278825-A | Sarcodictyin and eleutherobin useful for stabilising microtubules | NOVARTIS AG (CH) | 2001-01-03 | — | — | CN | disclosed |
| EP-1042328-A1 | SARCODICTYIN AND ELEUTHEROBIN DERIVATIVES USEFUL FOR STABILISING MICROTUBLES | Novartis AG (CH) | 2000-10-11 | — | — | EP | disclosed |
| US-5965718-A | Analogs of sarcodictyin and eleutherobin | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-10-12 | — | — | US | disclosed |
| WO-1999021862-A1 | SARCODICTYIN AND ELEUTHEROBIN USEFUL FOR STABILISING MICROTUBULES | NOVARTIS AG (CH) | 1999-05-06 | — | — | WO | disclosed |