⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862155 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL388497 | 0.74 | — | — | |
| SCHEMBL172783 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28031350 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL1454569 | 0.71 | — | — | |
| SCHEMBL856276 | 0.71 | — | — | |
| SCHEMBL28270615 | 0.71 | ALDH1A1 (0.47) | — | |
| SCHEMBL3994371 | 0.70 | — | — | |
| SCHEMBL676464 | 0.69 | — | — | |
| SCHEMBL621665 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 764 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037556-A1 | COMPOUNDS AND METHODS FOR INDUCING BROWNING OF WHITE ADIPOSE TISSUE | BEIJING ERAI THERAPEUTICS CO., LTD. (CN) | 2018-02-08 | — | — | US | claimed |
| CN-116134035-B | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119528910-A | Carboxyl condensed ring derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2024149359-A1 | PHENYL-SUBSTITUTED HETEROARYL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2024-07-18 | — | — | WO | disclosed |
| CN-118344325-A | PI3K selective inhibitors | 轩竹生物科技股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118344289-A | Phenyl substituted heteroaryl compound, and pharmaceutical composition, preparation method and application thereof | 上海美悦生物科技发展有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113195441-B | Androgen receptor modulators and methods of use thereof | 埃萨制药股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2024148150-A1 | SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES | Mirati Therapeutics, Inc. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-20240228482-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| EP-1215208-A2 | 4-Aminothiazole derivatives, their preparation and their use as inhibitors of cyclin-dependent kinases | Agouron Pharmaceuticals, Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2002024682-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-28 | — | — | WO | disclosed |
| EP-1056732-A2 | 4-AMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASES | AGOURON PHARMACEUTICALS, INC. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999021845-A2 | 4-AMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASES | AGOURON PHARMACEUTICALS, INC. (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5354772-A | Anticholesterol agents | SANDOZ PHARM. CORP. (US) | 1994-10-11 | — | — | US | disclosed |
| US-5272265-A | 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems | ELI LILLY AND COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| US-5179088-A | Administering bactericides | ELI LILLY AND COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
| EP-0445925-A1 | 1-Carba(dethia)caphalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4876280-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS; ANTILIPEMICS | SANDOZ PHARM. CORP. (US) | 1989-10-24 | — | — | US | disclosed |
| US-4739073-A | ANTICHOLESTEROL AGENTS | SANDOZ PHARMACEUTICALS CORP. (US) | 1988-04-19 | — | — | US | disclosed |