Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27671785 | 0.85 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL13853231 | 0.84 | KDM4E (0.50) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL30185608 | 0.83 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL19667440 | 0.82 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL5263170 | 0.81 | GABRP (0.55) | NPC1RAB9ASMN1; SMN2NNMTHPGD | |
| SCHEMBL9956693 | 0.77 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL26661375 | 0.77 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL31565499 | 0.77 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL12500156 | 0.77 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL23554282 | 0.75 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140845-B1 | SUSBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-02-23 | — | — | EP | disclosed |
| CN-1176907-C | Substituted pyridine herbicides | �����ɷ� | 2004-11-24 | — | — | CN | disclosed |
| US-6673938-B1 | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-06 | — | — | US | disclosed |
| US-6534445-B1 | Pyridine ketones for controlling weeds | SYNGENTA PARTICIPATIONS AG (CH) | 2003-03-18 | — | — | US | disclosed |
| US-20030040437-A1 | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2003-02-27 | — | — | US | disclosed |
| EP-1140845-A1 | SUSBSTITUTED PYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039094-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040437-A1 | Substituted pyridine herbicides | DDT, CYP1A1, CYP1B1 | NPC1 4516/4885RAB9A 3251/4885SMN1; SMN2 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.