SCHEMBL6060229

SCHEMBL6060229

COC(=O)C1CCCC=N1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM3 P20309 1/20 0.32
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31
MAPT P10636 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28615638 0.93 SMN1; SMN2 (0.37) SMN1; SMN2
SCHEMBL27899843 0.88
SCHEMBL17675561 0.80 MAPK1 (0.34) CHRM2CHRM3
SCHEMBL931732 0.79
SCHEMBL574892 0.75
SCHEMBL13130776 0.75
SCHEMBL18631750 0.74 FKBP1A (0.31)
SCHEMBL6217231 0.74
SCHEMBL18631746 0.73 POLB (0.34) MAPTTP53
Hydrochloric Acid SCHEMBL9386785 0.72 CHRM2 (0.35) CHRM2CHRM4CHRM3PPM1BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1655070-B1 OXIDATION CATALYST ASAHI KASEI CHEMICALS CORP (JP) 2015-07-15 EP disclosed
EP-1655070-A1 OXIDATION CATALYST Asahi Kasei Chemicals Corporation (JP) 2006-05-10 EP disclosed