Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.95 |
| ▸ | CA9 | Q16790 | 11/20 | 0.95 |
| ▸ | CA1 | P00915 | 7/20 | 0.95 |
| ▸ | CA3 | P07451 | 7/20 | 0.95 |
| ▸ | CA4 | P22748 | 7/20 | 0.95 |
| ▸ | CA7 | P43166 | 7/20 | 0.95 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.95 |
| ▸ | CA5A | P35218 | 6/20 | 0.95 |
| ▸ | CA6 | P23280 | 6/20 | 0.95 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.95 |
| ▸ | CA2 | P00918 | 5/20 | 0.95 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.95 |
| ▸ | LMNA | P02545 | 3/20 | 0.95 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.95 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL8144767 | 1.00 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL28077221 | 0.98 | CA12 (0.91) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL6252 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL3441294 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL29385611 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL621751 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL1038138 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL28886137 | 0.98 | CA12 (1.00) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL4958503 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 | |
| Coumarin SCHEMBL22721260 | 0.95 | CA12 (0.95) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105345-B | Benzofuran substituted coumarin amine derivative and application thereof in pollution resistance | 扬州工业职业技术学院 | 2020-07-17 | — | — | CN | claimed |
| EP-2486078-B1 | A LATENT CURING AGENT AND EPOXY COMPOSITIONS CONTAINING THE SAME | HENKEL AG & CO KGAA (DE) | 2018-02-21 | — | — | EP | claimed |
| CN-104311543-B | A kind of synthesis and application of the tri-arylamine group dye sensitizing agent containing cumarin | 浙江工业大学 | 2017-07-07 | — | — | CN | claimed |
| WO-2017044043-A1 | PROCESS FOR DIRECT AMIDATION OF AMINES VIA RH(I)-CATALYZED ADDITION OF BOROXINES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-03-16 | — | — | WO | claimed |
| US-9334426-B2 | Latent curing agent and epoxy compositions containing the same | HENKEL AG & CO. KGAA (DE) | 2016-05-10 | — | — | US | claimed |
| CN-104311543-A | Synthesis and application of coumarin-containing triarylamine dye sensitizing agent | UNIV ZHEJIANG TECHNOLOGY | 2015-01-28 | — | — | CN | claimed |
| US-20140235738-A1 | LATENT CURING AGENT AND EPOXY COMPOSITIONS CONTAINING THE SAME | HENKEL AG & CO. KGAA (DE) | 2014-08-21 | — | — | US | claimed |
| US-20120238653-A1 | LATENT CURING AGENT AND EPOXY COMPOSITIONS CONTAINING THE SAME | HENKEL AG & CO. KGAA (DE) | 2012-09-20 | — | — | US | claimed |
| EP-2486078-A1 | A LATENT CURING AGENT AND EPOXY COMPOSITIONS CONTAINING THE SAME | Henkel AG & Co. KGaA (DE) | 2012-08-15 | — | — | EP | claimed |
| WO-2011042062-A1 | A LATENT CURING AGENT AND EPOXY COMPOSITIONS CONTAINING THE SAME | HENKEL AG & CO. KGAA (DE) | 2011-04-14 | — | — | WO | claimed |
| CN-121494817-A | Coumarin nitrogen-containing heterocyclic derivative and application thereof in antidiabetic activity | 山西医科大学 | 2026-02-10 | — | — | CN | disclosed |
| EP-4585267-A2 | COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS | The University of Kansas (US) | 2025-07-16 | — | — | EP | disclosed |
| EP-3068778-B1 | COUMARIN BASED HSP90 INHIBITORS WITH UREA AND ETHER SUBSTITUENTS | UNIV KANSAS (US) | 2025-02-19 | — | — | EP | disclosed |
| WO-2024123412-A1 | FERROPTOSIS INDUCERS TO TREAT CANCER | THE UNIVERSITY OF TOLEDO (US) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024055291-A1 | METHOD FOR HIGH-THROUGHPUT SCREENING OF SIRTUIN MUTANT, SIRTUIN MUTANT, AND USE THEREOF | 中国科学院深圳先进技术研究院 | 2024-03-21 | — | — | WO | disclosed |
| US-6342379-B1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-01-29 | — | — | US | disclosed |
| WO-2001042211-A2 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-06-14 | — | — | WO | disclosed |
| US-6054114-A | DIAGNOSING THE DEGREE OF PROGRESSION OF ALZHEIMER'S DISEASE IN A MAMMAL, MONITORING THE RESPONSE TO A THERAPY IN A MAMMAL HAVING ALZHEIMER'S DISEASE, IDENTIFYING AN AGENT USEFUL FOR TREATING ALZHEIMER'S DISEASE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-04-25 | — | — | US | disclosed |
| WO-1997041856-A9 | ORGANOMETALLIC LIGANDS FOR THE LOCALIZATION AND QUANTIFICATION OF AMYLOID IN VIVO AND $i(IN VITRO) | — | 1998-10-01 | — | — | WO | disclosed |
| WO-1997041856-A1 | ORGANOMETALLIC LIGANDS FOR THE LOCALIZATION AND QUANTIFICATION OF AMYLOID IN VIVO AND $i(IN VITRO) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1997-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238653-A1 | LATENT CURING AGENT AND EPOXY COMPOSITIONS CONTAINING THE SAME | MCM7, CES2, EPHX2 | CA12 2268/4885CA9 2233/4885CA1 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.