Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 5/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.48 |
| ▸ | ITGAL | P20701 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222314 | 0.89 | ITGB2 (0.45) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL7064969 | 0.84 | ITGB2 (0.49) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL5830373 | 0.83 | ITGB2 (0.56) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6220880 | 0.78 | ITGB2 (0.53) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6220454 | 0.78 | ITGB2 (0.42) | ITGB2ICAM1ITGALALDH1A1KMT2A | |
| SCHEMBL6219369 | 0.75 | ITGB2 (0.47) | ITGB2ICAM1ITGALKMT2AL3MBTL1 | |
| SCHEMBL6913718 | 0.75 | ITGB2 (0.56) | ITGB2ICAM1ITGALKMT2AL3MBTL1 | |
| SCHEMBL6198401 | 0.74 | ITGB2 (0.54) | ITGB2ICAM1ITGALKMT2AL3MBTL1 | |
| SCHEMBL6221358 | 0.74 | RAB9A (0.40) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6201452 | 0.73 | ITGB2 (0.53) | ITGB2ICAM1ITGALALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |