Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.49 |
| ▸ | ITGAL | P20701 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217665 | 0.84 | ITGB2 (0.48) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL6222314 | 0.81 | ITGB2 (0.45) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL6913718 | 0.81 | ITGB2 (0.56) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL6220454 | 0.79 | ITGB2 (0.42) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL7064971 | 0.79 | RAB9A (0.47) | KMT2ARAB9ANPC1MEN1CYP1A2 | |
| SCHEMBL6220880 | 0.74 | ITGB2 (0.53) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL5830373 | 0.73 | ITGB2 (0.56) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL6139462 | 0.73 | ITGB2 (0.56) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL6139465 | 0.73 | ITGB2 (0.56) | ITGB2ICAM1ITGALKMT2ARAB9A | |
| SCHEMBL13879686 | 0.73 | ITGB2 (0.52) | ITGB2ICAM1ITGALKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |