Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 20/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 20/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6784837 | 0.99 | ADRA1D (0.66) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6735531 | 0.76 | ADRA1A (1.00) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6735535 | 0.76 | ADRA1A (1.00) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6270146 | 0.76 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6194108 | 0.76 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| SCHEMBL5660436 | 0.75 | ADRA1A (0.74) | ADRA1DADRA1AADRA1B | |
| SCHEMBL13939624 | 0.75 | ADRA1D (0.70) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6201215 | 0.74 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7681103 | 0.72 | ADRA1A (0.71) | ADRA1DADRA1AADRA1B | |
| SCHEMBL3988767 | 0.71 | ADRA1A (0.67) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021185-A4 | DIDHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 2005-09-07 | — | — | EP | disclosed |
| EP-1021185-A1 | DIDHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1997042956-A1 | DIDHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |