Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218779 | 0.92 | NPC1 (0.45) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL6220749 | 0.90 | HTT (0.51) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL6199838 | 0.86 | ALDH1A1 (0.52) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL6218162 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL6265119 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MAPTCYP1A2CYP2C19POLB | |
| SCHEMBL6217834 | 0.83 | NPC1 (0.41) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL6220677 | 0.82 | POLB (0.40) | ALDH1A1MAPTKDM4EHTTPOLB | |
| SCHEMBL6196369 | 0.82 | HTT (0.49) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E | |
| SCHEMBL6219884 | 0.81 | ITGAL (0.40) | MAPTKDM4EKMT2A | |
| SCHEMBL6198452 | 0.80 | KDM4E (0.47) | ALDH1A1MAPTCYP1A2CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |