SCHEMBL621817

SCHEMBL621817

CCCCOC(=O)c1cc(CCCC)ccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.54
TDP1 Q9NUW8 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KAT8 Q9H7Z6 2/20 0.54
PPARA Q07869 2/20 0.54
PPARG P37231 1/20 0.53
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
MAPK1 P28482 2/20 0.52
TP53 P04637 1/20 0.49
HSD17B10 Q99714 1/20 0.48
LMNA P02545 1/20 0.48
METAP2 P50579 1/20 0.47
KDM4E B2RXH2 1/20 0.46
RARB P10826 3/20 0.46
RARA P10276 1/20 0.46
RARG P13631 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4628347 0.93 TSHR (0.63) TSHRTDP1L3MBTL1KAT8PPARA
Octane SCHEMBL28824317 0.92 KAT8 (0.62) TSHRKAT8PPARAPPARGALDH1A1
SCHEMBL9420871 0.92 KAT8 (0.62) TSHRKAT8PPARAPPARGALDH1A1
Pentane SCHEMBL27636475 0.91 KAT8 (0.60) TSHRKAT8PPARAPPARGALDH1A1
SCHEMBL11573572 0.90 TSHR (0.55) TSHRTDP1L3MBTL1KAT8PPARA
SCHEMBL5831344 0.87 TSHR (0.47) TSHRTDP1L3MBTL1KAT8PPARA
SCHEMBL7591182 0.87 TSHR (0.47) TSHRTDP1L3MBTL1KAT8PPARA
SCHEMBL27640498 0.87 TSHR (0.65) TSHRTDP1L3MBTL1KAT8PPARA
Octane SCHEMBL28857502 0.86 KAT8 (0.62) TSHRTDP1L3MBTL1KAT8PPARA
SCHEMBL182437 0.86 KAT8 (0.62) TSHRTDP1L3MBTL1KAT8PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085749-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
CN-117288848-A Neovascular senile macular degeneration diagnostic marker and application thereof 中南大学湘雅二医院 2023-12-26 CN disclosed
CN-107868149-A A kind of catalytic component, catalyst and its application for olefinic polymerization 中国石油化工股份有限公司 2018-04-03 CN disclosed
CN-107868147-A A kind of catalytic component, catalyst and its application for olefinic polymerization 中国石油化工股份有限公司 2018-04-03 CN disclosed
CN-105085749-B Catalytic component and its catalyst for propylene polymerization 中国石油化工股份有限公司 2017-12-19 CN disclosed
CN-105085749-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN disclosed
EP-2603565-A2 LATEX COATING COMPOSITIONS INCLUDING CARBOXY ESTER KETAL COALESCENTS, METHODS OF MANUFACTURE, AND USES THEREOF Segetis, Inc. (US) 2013-06-19 EP disclosed
WO-2012021826-A2 LATEX COATING COMPOSITIONS INCLUDING CARBOXY ESTER KETAL COALESCENTS, METHODS OF MANUFACTURE, AND USES THEREOF SEGETIS, INC. (US) 2012-02-16 WO disclosed