Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831344 | 0.88 | TSHR (0.47) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL621817 | 0.87 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11573572 | 0.83 | TSHR (0.55) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9420871 | 0.82 | KAT8 (0.62) | TSHRALDH1A1MAPK1CYP3A4PPARA | |
| Octane SCHEMBL28824317 | 0.82 | KAT8 (0.62) | TSHRALDH1A1MAPK1CYP3A4PPARA | |
| Pentane SCHEMBL27636475 | 0.81 | KAT8 (0.60) | TSHRALDH1A1MAPK1CYP3A4PPARA | |
| SCHEMBL4628347 | 0.80 | TSHR (0.63) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL13737267 | 0.79 | TSHR (0.61) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| Azetidine SCHEMBL28757441 | 0.79 | KAT8 (0.54) | TSHRALDH1A1MAPK1CYP3A4PPARA | |
| SCHEMBL4949933 | 0.79 | ALDH1A1 (0.59) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020165234-A1 | Selective B3 adrenergic agonists | CROWELL THOMAS A (US) | 2002-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165234-A1 | Selective B3 adrenergic agonists | ADRB3, ADRB2, ADRB1 | TSHR 247/4885TDP1 3833/4885L3MBTL1 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.