Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576971 | 0.88 | KCNH2 (0.37) | KCNH2MAPTMEN1KMT2ADRD2 | |
| SCHEMBL6215704 | 0.85 | CA12 (0.41) | ALDH1A1MEN1KMT2AATMKDM4E | |
| SCHEMBL6220871 | 0.84 | MAPT (0.35) | KCNH2MAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL3337171 | 0.81 | KCNH2 (0.41) | KCNH2TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL141817 | 0.77 | TOP2A (0.33) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL141441 | 0.77 | KCNH2 (0.31) | KCNH2DRD2 | |
| SCHEMBL4466379 | 0.76 | P2RX7 (0.34) | KCNH2MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL7100426 | 0.73 | KCNH2 (0.54) | KCNH2TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL4297278 | 0.70 | KCNH2 (0.34) | KCNH2MAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL143726 | 0.70 | TOP2A (0.39) | KCNH2MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343766-B1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | PROCTER & GAMBLE (US) | 2005-07-27 | — | — | EP | disclosed |