Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218172 | 0.84 | PTPN1 (0.50) | PTPN1PTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL6218960 | 0.82 | PTPN1 (0.48) | PTPN1PTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL5395054 | 0.81 | ALDH1A1 (0.51) | KMT2APTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL4296500 | 0.79 | ALKBH1 (0.52) | KMT2APTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL6216202 | 0.76 | KMT2A (0.47) | KMT2APTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL1195916 | 0.76 | NPC1 (0.47) | KMT2APTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL6218321 | 0.76 | PTPN1 (0.43) | PTPN1KMT2AALDH1A1MEN1 | |
| SCHEMBL5406901 | 0.76 | KDM4E (0.57) | KMT2APTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL720149 | 0.75 | NPSR1 (0.58) | KMT2AALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL4847074 | 0.74 | ALDH1A1 (0.54) | KMT2APTGS2PTGS1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |