Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177139 | 0.83 | DRD3 (0.44) | DRD3ALDH1A1CA12CA9TRPA1 | |
| SCHEMBL6050329 | 0.78 | NR1H2 (0.46) | DRD3ALDH1A1CA12CA9NR1H2 | |
| SCHEMBL8332447 | 0.77 | NR1H2 (0.49) | ALDH1A1CA12CA9NR1H2NR1H3 | |
| SCHEMBL6214680 | 0.77 | DRD3 (0.40) | DRD3ALDH1A1CA12CA9TRPA1 | |
| SCHEMBL8331683 | 0.77 | NR1H2 (0.49) | ALDH1A1CA12CA9NR1H2NR1H3 | |
| SCHEMBL8328628 | 0.77 | NR1H2 (0.49) | ALDH1A1CA12CA9NR1H2NR1H3 | |
| SCHEMBL6329301 | 0.75 | DRD3 (0.43) | DRD3ALDH1A1CA12CA9GAA | |
| SCHEMBL900640 | 0.73 | DRD3 (0.46) | DRD3ALDH1A1CA12CA9NR1H2 | |
| SCHEMBL6837085 | 0.71 | ALDH1A1 (0.40) | DRD3ALDH1A1CA12CA9GAA | |
| SCHEMBL27473685 | 0.69 | ALDH1A1 (0.40) | DRD3ALDH1A1CA12CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839149-B9 | GALANTHAMINE DERIVATIVES, PREPARATION METHOD THEREFOR, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | CT NAT DELA RECH SCIENT (FR) | 2005-03-09 | — | — | EP | disclosed |
| EP-0839149-B1 | GALANTHAMINE DERIVATIVES, PREPARATION METHOD THEREFOR, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | CT NAT DELA RECH SCIENT (FR) | 2004-04-14 | — | — | EP | disclosed |