Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 9/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.57 |
| ▸ | CCNC | P24863 | 5/20 | 0.46 |
| ▸ | CDK8 | P49336 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219402 | 0.91 | ITGB2 (0.47) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6219690 | 0.90 | ITGB2 (0.47) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6220322 | 0.89 | ITGB2 (0.46) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6219767 | 0.89 | NPC1 (0.47) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6219918 | 0.86 | CCNC (0.46) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6197437 | 0.85 | ITGAL (0.66) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6219332 | 0.81 | HTT (0.52) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6311964 | 0.78 | ITGAL (0.77) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6197403 | 0.77 | ITGAL (0.55) | ITGALITGB2ICAM1CCNCCDK8 | |
| SCHEMBL6221788 | 0.76 | ITGAL (0.42) | ITGALITGB2ICAM1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |