Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.47 |
| ▸ | ITGAL | P20701 | 4/20 | 0.47 |
| ▸ | CCNC | P24863 | 3/20 | 0.42 |
| ▸ | CDK8 | P49336 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218982 | 0.90 | ITGAL (0.57) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6219332 | 0.89 | HTT (0.52) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6198429 | 0.86 | ITGB2 (0.54) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6219918 | 0.85 | CCNC (0.46) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6219402 | 0.84 | ITGB2 (0.47) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6217580 | 0.84 | ITGB2 (0.50) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6220322 | 0.81 | ITGB2 (0.46) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6219767 | 0.81 | NPC1 (0.47) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6197269 | 0.79 | ITGAL (0.63) | ITGB2ICAM1ITGALCCNCCDK8 | |
| SCHEMBL6220670 | 0.78 | ITGAL (0.39) | ITGB2ICAM1ITGALHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |