Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 6/20 | 0.46 |
| ▸ | CDK8 | P49336 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.42 |
| ▸ | ITGAL | P20701 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218982 | 0.86 | ITGAL (0.57) | CCNCCDK8RAB9AITGB2ICAM1 | |
| SCHEMBL6219402 | 0.85 | ITGB2 (0.47) | CCNCCDK8RAB9AITGB2ICAM1 | |
| SCHEMBL6219690 | 0.85 | ITGB2 (0.47) | CCNCCDK8ALDH1A1RAB9AITGB2 | |
| SCHEMBL6202870 | 0.84 | ITGB2 (0.48) | CCNCCDK8ALDH1A1RAB9AITGB2 | |
| SCHEMBL6219767 | 0.82 | NPC1 (0.47) | CCNCCDK8ALDH1A1RAB9AITGB2 | |
| SCHEMBL6219332 | 0.81 | HTT (0.52) | CCNCCDK8ALDH1A1ITGB2ICAM1 | |
| SCHEMBL6220322 | 0.81 | ITGB2 (0.46) | CCNCCDK8RAB9AITGB2ICAM1 | |
| SCHEMBL6568699 | 0.72 | ITGAL (0.74) | CCNCCDK8ALDH1A1RAB9AITGB2 | |
| SCHEMBL6202872 | 0.72 | ITGAL (0.74) | CCNCCDK8ALDH1A1RAB9AITGB2 | |
| SCHEMBL6197437 | 0.72 | ITGAL (0.66) | CCNCCDK8RAB9AITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |