SCHEMBL6219210

SCHEMBL6219210

O=C1CCC2(CC2)C(=O)C1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
CYP2C9 P11712 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9660132 0.87 ALDH1A1 (0.33)
SCHEMBL1434776 0.76
SCHEMBL6173406 0.74
SCHEMBL11963724 0.70 TRIM24 (0.38) MEN1CYP2C9KMT2A
SCHEMBL992137 0.70
SCHEMBL9629481 0.70
SCHEMBL17995460 0.69 TRIM24 (0.43) MEN1CYP2C9KMT2A
Ethylene SCHEMBL15565110 0.67 TRIM24 (0.35) MEN1CYP2C9KMT2A
SCHEMBL11023410 0.65 ALDH1A1 (0.30)
SCHEMBL2002992 0.65 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295068-A1 NOVEL CYCLOALKENONE COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO., LTD. (JP) 2023-09-21 US disclosed
EP-4194435-A1 NOVEL CYCLOALKENONE COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2023-06-14 EP disclosed
CN-116096361-A Novel cyclic enone compound or salt thereof 大鹏药品工业株式会社 2023-05-09 CN disclosed
US-9890139-B2 CYP17 inhibitors/antiandrogens ORION CORPORATION (FI) 2018-02-13 US disclosed
US-20160130254-A1 NOVEL CYP17 INHIBITORS/ANTIANDROGENS ORION CORPORATION (FI) 2016-05-12 US disclosed
EP-3008042-A1 NOVEL CYP17 INHIBITORS/ANTIANDROGENS Orion Corporation (FI) 2016-04-20 EP disclosed
WO-2014202827-A1 NOVEL CYP17 INHIBITORS/ANTIANDROGENS ORION CORPORATION (FI) 2014-12-24 WO disclosed
EP-1140845-B1 SUSBSTITUTED PYRIDINE HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2005-02-23 EP disclosed
US-6673938-B1 Substituted pyridine herbicides SYNGENTA PARTICIPATIONS AG (CH) 2004-01-06 US disclosed
US-6534445-B1 Pyridine ketones for controlling weeds SYNGENTA PARTICIPATIONS AG (CH) 2003-03-18 US disclosed
US-20030040437-A1 Substituted pyridine herbicides SYNGENTA PARTICIPATIONS AG (CH) 2003-02-27 US disclosed
EP-1140845-A1 SUSBSTITUTED PYRIDINE HERBICIDES Syngenta Participations AG (CH) 2001-10-10 EP disclosed
WO-2000039094-A1 SUBSTITUTED PYRIDINE HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030040437-A1 Substituted pyridine herbicides DDT, CYP1A1, CYP1B1 MEN1 2310/4885CYP2C9 84/4885KMT2A 1588/4885
US-20160130254-A1 NOVEL CYP17 INHIBITORS/ANTIANDROGENS CYP17A1, CYP19A1, CYP21A2 MEN1 1462/4885CYP2C9 84/4885KMT2A 650/4885
US-20230295068-A1 NOVEL CYCLOALKENONE COMPOUND OR SALT THEREOF BDNF, SMN1; SMN2, ELAVL1 MEN1 4376/4885CYP2C9 4187/4885KMT2A 3058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.