Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201235 | 0.91 | EGLN1 (0.41) | EGLN1NR3C1AKR1B1LMNAPOLA1 | |
| SCHEMBL6197241 | 0.91 | EGLN1 (0.43) | EGLN1NR3C1LMNAPOLA1GSK3B | |
| SCHEMBL6199909 | 0.91 | EGLN1 (0.43) | EGLN1NR3C1LMNAPOLA1GSK3B | |
| SCHEMBL6198205 | 0.89 | EGLN1 (0.42) | EGLN1NR3C1LMNAPOLA1GSK3B | |
| SCHEMBL6218719 | 0.88 | EGLN1 (0.44) | EGLN1NR3C1LMNAPOLA1GSK3B | |
| SCHEMBL6201372 | 0.88 | EGLN1 (0.41) | EGLN1NR3C1LMNAPOLA1GSK3B | |
| SCHEMBL6197493 | 0.88 | LMNA (0.44) | EGLN1NR3C1LMNAPOLA1GSK3B | |
| SCHEMBL6196660 | 0.88 | NR3C1 (0.42) | EGLN1NR3C1LMNAPOLA1GSK3B | |
| SCHEMBL6199593 | 0.86 | EGLN1 (0.39) | EGLN1NR3C1AKR1B1LMNAPOLA1 | |
| SCHEMBL6201822 | 0.86 | NR3C1 (0.42) | EGLN1NR3C1LMNAPOLA1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |