Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 9/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093419 | 0.80 | MC4R (0.69) | MC4R | |
| SCHEMBL13723873 | 0.68 | MC4R (0.55) | MC4R | |
| SCHEMBL3093411 | 0.67 | MC4R (0.72) | MC4R | |
| SCHEMBL3082128 | 0.67 | MCL1 (0.54) | MC4RMTNR1A | |
| SCHEMBL13725011 | 0.66 | MC4R (0.47) | MC4RMTNR1A | |
| SCHEMBL6222879 | 0.65 | MC4R (0.54) | MC4R | |
| SCHEMBL3093429 | 0.63 | MC4R (0.54) | MC4RMTNR1A | |
| SCHEMBL3095690 | 0.62 | KDM4E (0.48) | MC4R | |
| SCHEMBL30344504 | 0.59 | MEN1 (0.61) | MTNR1A | |
| SCHEMBL29357161 | 0.59 | MTNR1A (0.55) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590338-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | Gene Logic Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004050610-A2 | MODULATORS OF MELANOCORTIN RECEPTOR | GENE LOGIC INC. (US) | 2004-06-17 | — | — | WO | disclosed |