Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ITGAL | P20701 | 5/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220267 | 0.92 | ITGAL (0.52) | RAB9AALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6221015 | 0.88 | ALPL (0.47) | RAB9AALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6222576 | 0.85 | ITGAL (0.43) | RAB9AALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6216341 | 0.82 | KDM4E (0.58) | ALDH1A1ITGALITGB2ICAM1GAA | |
| SCHEMBL5830729 | 0.80 | ITGAL (0.64) | RAB9AALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6218886 | 0.80 | ENPP2 (0.42) | RAB9AALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL6219235 | 0.79 | ITGAL (0.42) | RAB9AALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL7613155 | 0.79 | ITGAL (0.54) | RAB9AALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6218000 | 0.76 | SMN1; SMN2 (0.45) | RAB9AALDH1A1ITGALITGB2ICAM1 | |
| SCHEMBL6214988 | 0.75 | ITGAL (0.39) | RAB9AALDH1A1ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |