SCHEMBL6222233

SCHEMBL6222233

CCC(=O)O[C@@H]1[C@H](OC(=O)CC)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.58
SLC28A2 O43868 1/20 0.58
SLC29A1 Q99808 1/20 0.58
SLC28A3 Q9HAS3 1/20 0.58
TK2 O00142 2/20 0.45
P2RY2 P41231 9/20 0.44
P2RY6 Q15077 6/20 0.44
P2RY14 Q15391 2/20 0.44
P2RY4 P51582 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13901219 1.00 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3TK2
SCHEMBL13901223 0.92 SLC28A1 (0.50) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL23247861 0.90 SLC28A1 (0.55) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL23247860 0.90 SLC28A1 (0.55) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5074670 0.90 LMNA (0.48) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL6545745 0.90 SLC28A1 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL6226229 0.90 SLC28A1 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL2921711 0.90 SLC28A1 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL25924676 0.90 SLC28A1 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL26644222 0.90 SLC28A1 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894868-B1 Process for producing nucleoside derivatives SUMITOMO CHEMICAL CO (JP) 2005-03-16 EP disclosed
US-6127152-A CONTACTING 2',3',5'-O-TRIACYLRIBONUCLEOSIDE DERIVATIVE WITH AN ESTER HYDROLASE OF A SPECIFIC AMINO ACID SEQUENCE TO REGIO-SELECTIVELY DEACYLATE THE ACYL GROUP AT THE 5'-O-POSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-03 US disclosed
EP-0894868-A2 Process for producing nucleoside derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-03 EP disclosed