Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 7/20 | 0.51 |
| ▸ | FSHR | P23945 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 11/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030984 | 0.92 | BRAF (0.57) | LHCGRFSHRBRAFPDE4APDE4B | |
| SCHEMBL5026187 | 0.88 | LHCGR (0.52) | LHCGRFSHRBRAFTSHRCHRM4 | |
| SCHEMBL6223594 | 0.88 | LHCGR (0.49) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL6222004 | 0.86 | LHCGR (0.68) | LHCGRFSHRBRAFTSHR | |
| SCHEMBL5028901 | 0.83 | LHCGR (0.54) | LHCGRFSHRBRAFTSHRCHRM4 | |
| SCHEMBL5028895 | 0.83 | LHCGR (0.54) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL5024674 | 0.82 | LHCGR (0.59) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL6220667 | 0.82 | LHCGR (0.53) | LHCGRFSHRBRAFTSHR | |
| SCHEMBL4426367 | 0.79 | LHCGR (0.55) | LHCGRFSHRBRAFTSHRCHRM4 | |
| SCHEMBL6224284 | 0.79 | LHCGR (0.50) | LHCGRFSHRBRAFTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427734-B1 | GLYCINE-SUBSTITUTED THIENO[2,3-d]PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY | AKZO NOBEL NV (NL) | 2005-11-09 | — | — | EP | claimed |