Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13927631 | 0.83 | ALDH1A1 (0.45) | PTGDR2KDM4EALDH1A1TBXA2RPTGDR | |
| SCHEMBL6222657 | 0.82 | PTGER1 (0.39) | PTGDR2CSNK1EPTGER1HCRTR1HCRTR2 | |
| SCHEMBL4140254 | 0.76 | PDE4A (0.39) | KDM4EALDH1A1GRIN2BMAPK1PTGER1 | |
| SCHEMBL4146332 | 0.71 | KDM4E (0.45) | PTGDR2KDM4ETBXA2RPTGDRCSNK1E | |
| SCHEMBL6223386 | 0.71 | TRPA1 (0.49) | PTGDR2KDM4EGRIN2BMAPK1 | |
| SCHEMBL2857932 | 0.71 | PTGER1 (0.41) | ALDH1A1CSNK1EPTGER1 | |
| SCHEMBL27536115 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPK1PTGER1 | |
| SCHEMBL4145901 | 0.70 | MAPK1 (0.38) | KDM4EALDH1A1MAPK1PTGER1 | |
| SCHEMBL4137268 | 0.70 | DPP4 (0.42) | KDM4EALDH1A1MAPK1CSNK1EPTGER1 | |
| SCHEMBL2865256 | 0.69 | PTGER1 (0.41) | KDM4EALDH1A1CSNK1EPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1656079-A | Pyrazole compounds and pharmaceutical compositions containing the same | EISAI CO LTD (JP) | 2005-08-17 | — | — | CN | disclosed |
| EP-1510516-A1 | PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |