Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 8/20 | 0.48 |
| ▸ | FSHR | P23945 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030956 | 0.91 | BRAF (0.47) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5026958 | 0.88 | LHCGR (0.51) | LHCGRFSHRTSHRMAPTMEN1 | |
| SCHEMBL6222882 | 0.87 | LHCGR (0.48) | LHCGRFSHRTSHRMAPTMEN1 | |
| SCHEMBL6222764 | 0.86 | LHCGR (0.52) | LHCGRFSHRTSHRMEN1KMT2A | |
| SCHEMBL6223594 | 0.86 | LHCGR (0.49) | LHCGRFSHRTSHRMAPTMEN1 | |
| SCHEMBL5030864 | 0.85 | LHCGR (0.68) | LHCGRFSHRTSHRBRAF | |
| SCHEMBL6224121 | 0.84 | LHCGR (0.51) | LHCGRFSHRTSHRMAPTMEN1 | |
| SCHEMBL5026952 | 0.84 | LHCGR (0.49) | LHCGRFSHRTSHRMEN1KMT2A | |
| SCHEMBL5024691 | 0.82 | LHCGR (0.57) | LHCGRFSHRTSHRMAPTMEN1 | |
| SCHEMBL6224284 | 0.81 | LHCGR (0.50) | LHCGRFSHRTSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427734-B1 | GLYCINE-SUBSTITUTED THIENO[2,3-d]PYRIMIDINES WITH COMBINED LH AND FSH AGONISTIC ACTIVITY | AKZO NOBEL NV (NL) | 2005-11-09 | — | — | EP | claimed |