Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481612 | 0.78 | MAPT (0.35) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL12815928 | 0.73 | MAPT (0.35) | MAPTLMNAHTTKMT2AHSD17B10 | |
| SCHEMBL1629378 | 0.72 | MAPT (0.37) | MAPTLMNAHTTKMT2AHSD17B10 | |
| SCHEMBL9701635 | 0.72 | LMNA (0.50) | MAPTLMNAHTTKMT2AHSD17B10 | |
| SCHEMBL5145616 | 0.72 | LMNA (0.50) | MAPTLMNAHTTKMT2AHSD17B10 | |
| SCHEMBL12348879 | 0.72 | LMNA (0.45) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL9453784 | 0.72 | MAPT (0.40) | MAPTLMNAHTTKMT2AHSD17B10 | |
| SCHEMBL8618279 | 0.70 | LMNA (0.48) | MAPTLMNAHTTKMT2AHSD17B10 | |
| SCHEMBL9228160 | 0.70 | LMNA (0.39) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL7920838 | 0.68 | LMNA (0.37) | MAPTLMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352043-B1 | IMPROVED CONTINUOUSLY OPERATING PRESS UTILIZING A PHENYL-ENDBLOCKED POLYDIORGANOSILOXANE-POLPHENYLORGANOSILOXANE RANDOM COPOLYMER FLUID | DOW CORNING (US) | 2005-03-16 | — | — | EP | disclosed |
| EP-1352043-A1 | IMPROVED CONTINUOUSLY OPERATING PRESS UTILIZING A PHENYL-ENDBLOCKED POLYDIORGANOSILOXANE-POLPHENYLORGANOSILOXANE RANDOM COPOLYMER FLUID | Dow Corning Corporation (US) | 2003-10-15 | — | — | EP | disclosed |
| US-6530316-B2 | Continuously operating press utilizing a phenyl-endblocked polydiorganosiloxane-polyphenylorganosiloxane random copolymer fluid | DOW CORNING CORPORATION | 2003-03-11 | — | — | US | disclosed |
| US-20020129718-A1 | Continuously operating press utilizing a phenyl-endblocked polydiorganosiloxane-polyphenylorganosiloxane random copolymer fluid | DOW CORNING CORPORATION | 2002-09-19 | — | — | US | disclosed |
| WO-2002066586-A1 | IMPROVED CONTINUOUSLY OPERATING PRESS UTILIZING A PHENYL-ENDBLOCKED POLYDIORGANOSILOXANE-POLPHENYLORGANOSILOXANE RANDOM COPOLYMER FLUID | DOW CORNING CORPORATION (US) | 2002-08-29 | — | — | WO | disclosed |