Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | AKT2 | P31751 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453784 | 0.91 | MAPT (0.40) | MAPTHTTLMNAAKT2BRD4 | |
| SCHEMBL7533650 | 0.83 | MAPT (0.35) | MAPTHTTLMNAAKT2BRD4 | |
| SCHEMBL9092306 | 0.83 | NPC1 (0.42) | MAPTLMNAALDH1A1KMT2AACHE | |
| SCHEMBL9319071 | 0.78 | ESR1 (0.41) | MAPTLMNAAKT2BRD4CHEK1 | |
| SCHEMBL9701635 | 0.77 | LMNA (0.50) | MAPTHTTLMNAAKT2BRD4 | |
| SCHEMBL8618279 | 0.75 | LMNA (0.48) | MAPTHTTLMNAAKT2BRD4 | |
| SCHEMBL6294085 | 0.75 | LMNA (0.48) | MAPTHTTLMNAAKT2BRD4 | |
| SCHEMBL27619559 | 0.75 | LMNA (0.48) | MAPTHTTLMNAAKT2BRD4 | |
| SCHEMBL12815928 | 0.74 | MAPT (0.35) | MAPTHTTLMNAAKT2BRD4 | |
| SCHEMBL8481612 | 0.74 | MAPT (0.35) | MAPTHTTLMNAAKT2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163863-B2 | Polysilane and polysilane-containing resin composition | OSAKA GAS CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20110253929-A1 | MIXTURES OF HYDROPHOBIC AND HYDROPHILIC IONIC LIQUIDS AND USE THEREOF IN LIQUID RING COMPRESSORS | BASF SE (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20110089384-A1 | HIGHLY COMPATIBLE AND NON-MIGRATORY POLYMERIC UV-ABSORBER | LAZZARI DARIO | 2011-04-21 | — | — | US | disclosed |
| US-20100081798-A1 | METHOD FOR PRODUCING GLUCOSE BY ENZYMATIC HYDROLYSIS OF CELLULOSE THAT IS OBTAINED FROM MATERIAL CONTAINING LIGNO-CELLULOSE USING AN IONIC LIQUID THAT COMPRISES A POLYATOMIC ANION | BASF SE (DE) | 2010-04-01 | — | — | US | disclosed |
| US-20090156775-A1 | POLYSILANE AND POLYSILANE-CONTAINING RESIN COMPOSITION | OSAKA GAS CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20060235116-A1 | Highly compatible and non-migratory polymeric uv-absorber | CIBA SPECIALTY CHEMICALS CORP. | 2006-10-19 | — | — | US | disclosed |
| US-20050059758-A1 | Transparent polymer articles of low thickness | LEPPARD DAVID GEORGE (CH) | 2005-03-17 | — | — | US | disclosed |
| US-6626990-B2 | Using aromatic- or heteraromatic-compounds having at least one hydroxyl or keto group bonded to the ring, with the oxidation of corresponding dihydroquinacridone salts | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081798-A1 | METHOD FOR PRODUCING GLUCOSE BY ENZYMATIC HYDROLYSIS OF CELLULOSE THAT IS OBTAINED FROM MATERIAL CONTAINING LIGNO-CELLULOSE USING AN IONIC LIQUID THAT COMPRISES A POLYATOMIC ANION | MGAM, LCT, SI | MAPT 1844/4885HTT 4521/4885LMNA 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.